Adverse effects of topoisomerase inhibitor might include:
• Allergic reaction symptoms, such as fast heart beat and sweating, itching or hives, swelling in the face (lips, tongue, throat) or hands, chest tightness, and wheezing, trouble breathing
• Unexplained fever, chills, or sore throat. Severe nausea, vomiting, or diarrhea with stomach pain, blood in stool or other signs of infection