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The epidermis, sweat glands, and blood vessels—the vents, condensers, and heat ducts of your body's heating and cooling system—all cooperate with the hypothalamus to regulate body temperature. Most of the body's water is stored in the dermis, the main layer of skin.

The excretory system and the circulatory system are interdependent because the excretory system filters the blood of the circulatory system. the kidneys' primary organ of the excretory system. The kidneys filter the blood as it travels through the circulatory system.

By assisting in the discharge of metabolic wastes, the excretory system interacts with the muscular system. Urine is the primary fluid produced by the excretory system.

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