A and B are linked genes. In a study of 100 offspring, 94 had parental genotypes for A and B, while 6 were recombinants. A and B are 6 centimorgans (cm) apart.
- Genes that are physically adjacent to one another on the same chromosome are said to be linked genes because they are more likely to be inherited together.
- Chromosomes are recombined during meiosis, causing gene swaps between homologous chromosomes.
- Together, they are inherited. For instance, certain eye and hair colors are inherited jointly and are related genetically.
- By dividing the total number of recombinant gametes by the total number of gametes, X 100 the linkage distance is determined.
Thus here the total recombinant genes are 6 and the total number of gametes or offspring are 100 so,
[(6/100) x 100]
= 0.06 x 100
= 6
Hence, A and B are 6 cm apart.
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