Some psychoactive drugs work as _, meaning that they artificially stimulate receptors in a neurotransmitter system. Others work as _, meaning that they block activity at particular receptors.

An agonist drug attaches to both the receptor which induces the reaction inside the cell. An antagonist can attach to the very same receptor, but will not generate a response, rather it stops the receptor from a natural agonist.

Antagonism can be successful and offset by elevated agonist levels. Unmanageable antagonists are firmly bound to a transmitter and therefore are not removed by an external agonist.

Some psychoactive drugs work as _______, meaning that they artificially stimulate receptors in a neurotransmitter system. Others work as _______, meaning that they block activity at particular receptors.

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Some psychoactive drugs work as _, meaning that they artificially stimulate receptors in a neurotransmitter system. Others work as _, meaning that they block activity at particular receptors.