It is possible to use molecular genetic techniques to characterize the T cells found in psoriasis plaques and compare them to the T cells found in healthy skin. In healthy skin, T cells have a wide diversity of T cell receptors. In other words, there are many different T cell clones found in healthy tissue. In psoriasis plaques, there are fewer T cell clones, but often there are a large number of T cells representing only a small number of clones (this is called oligoclonal expansion). There are usually many more T cells in total found in psoriasis plaques relative to healthy skin. Think about the implications of this finding. What conclusion is NOT supported by these findings

According to what has been investigated the option that should be supported by more scientific evidence: In psoriasis plaques, there are fewer T-cell clones, but there are often a large number of T-cells representing only a small number of clones (this is called oligoclonal expansion).

Explanation:

Oligoclonal expansion does not occur only in this pathology, it also occurs in other recurrent diseases such as multiple sclerosis, this phenomenon is widely studied and little discovered in some aspects and is mainly based on both tcd4 and tcd8 and b lymphocytes.

In this case, the presence of ltcd4 in psoriasis is very versatile and depends on the patient's immune response, which is why more scientific evidence is needed on this topic, based mostly on meta-analyzes.