Question

Where are the most active metals located on the periodic table

Answer 1

Do you mean to question where are the most reactive metals on the periodic table? In case, that would be group 1; the Alkali Metals.

Answer 2

The elements toward the bottom left corner of the periodic table are the metals that are the most active in the sense of being the most reactive. Lithium, sodium, and potassium all react with water, for example.