Question

What part of defense would likely be affected if the pathogen contained a mutation in it's pathogen-associated molecular patterns (PAMPs)?
Select one:
a. the pathogen would not be able to penetrate the host's physical barriers.
b. the pathogen would be easily recognized by the host's TLRs.
c. the pathogen would secrete greater amounts of toxins.
d. the pathogen might not be recognized by the host.

Answer 1

Answer:

The correct answer will be option D.

Explanation:

Pathogen-associated molecular patterns or PAMPs are the structural molecular motifs present in the microbes.

These molecules activate the immune system after they are recognized by the pattern recognition receptors and toll-like receptors. The host activates its immune system in response and becomes resistant to the pathogen.

If mutation takes place in the conserved sequence of the PAMP, they will not be recognized by the host and the host will not be able to trigger its immune response.

Thus, option D is the correct answer.