Thanks to the bull of Pope Paul III Sublimis Deus of 1537, who declared to the indigenous men with all the effects and abilities of Christians, there was a great contrast in America between the Spanish colonization and the French colonization with the Anglo-Saxon colonization: the Spaniards endeavored to incorporate the indigenous to their civilization and their Church, even at the expense of the annulment of their cultural identity.
One of the important consequences of this colonization was miscegenation in America. The Kings established a common foreign policy marked by matrimonial links with several European royal families that resulted in the hegemony of the Habsburgs in Europe during the sixteenth and seventeenth centuries. On the other hand, the discovery of America from 1492 profoundly changed history.