Sickle cell disease results from an amino acid change from Valentine to glutamic acid. The result of this amino acid change is a deformed hemoglobin protein that does not carry oxygen well. What type of genetic mutation caused the amino acid change in a person with sickle cell anemia?
a. frameshift mutation b. silent mutation c. nonsense mutation d. missense mutation
A- the whole protein would be off, not just one AA B- the disease wouldn’t occur C - nonsense would end up in a truncated protein ((so shorter protein)
