The resting membrane potential is dependent upon two important factors: 1) differences in sodium and potassium concentrations across the membrane (electrochemical gradients) and 2) differences in sodium and potassium membrane permeability. this activity will help you to review how the resting membrane potential of cells are generated and maintained. use the provided ions to correctly complete each sentence about the resting membrane potential. ions may be used more than once, or not at all.