Question

Antibodies, which are produced as part of the adaptive immune response, can sometimes be damaging rather than beneficial. people suffering from an autoimmune disease called antiphospholipid antibody syndrome (aps) make antibodies that bind to phospholipids. some of the signs and symptoms affected individuals experience are blood clots, stroke, heart attack, and kidney damage. what is the likely cause of these symptoms?

Answer 1

The symptoms associated with antiphospholipid antibody syndrome are caused by abnormal blood clots that occur when there is production of antibodies that damage phospholipids in the body. Phospholipids are needed in blood clotting whereas antibodies protect the body against bacteria and viruses. In severe cases, the abnormal blood clots can obstruct flow of blood to the affected organ and subsequently cause symptoms, such as high blood pressure, lung problems, heart damage, stroke, and kidney failure.