Question

where would the enzyme topoisomerase attach during dna replication?

Answer 1

When DNA replication occurs, the DNA strand is being unwound, causing the DNA to be overwound tightly past the replication fork.
For example, If you have ever wrapped two strings around each other and then tried to pull part the middle of the string while holding the ends tight, the rest of the string past the place you're pulling the string apart becomes very tight and strained.

Topoisomerase is an enzyme that binds to the DNA and helps release some of that strain by unwinding the DNA past the replication fork.

That means the correct box is the leftmost one. Hope this helps:)

Answer 2

The enzyme topoisomerase attaches to DNA in front of the replication fork.

What is topoisomerase ?

An enzyme which alters the supercoiled form of a DNA molecule.

What is replication fork ?

The replication fork is a structure that forms within the long helical DNA during DNA replication.

What is the function of topoisomerase  ?

Topoisomerases are crucial enzymes for many fundamental aspects of neural function. Their primary functions — to cleave DNA strands in order to provide torsional-stress relief or to untangle replicating DNA — provide essential cellular controls during replication and transcription.

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