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One of the differences is
dna is double stranded
rna is single stranded
The sugar present in a molecule of RNA is ribose
The sugar present in a molecule of 
DNA is deoxyribose.

DNA uses A-T (Adenine-Thymine), G-C (Guanine-Cytosine)
RNA uses A-U (Adenine-Uracil), G-C (Guanine-Cytosine)

DNA functions as a medium of long-term storage and transmission of genetic information.
RNA transfers the genetic code needed for the creation of proteins from the nucleus to the ribosome. This process prevents the DNA from having to leave the nucleus, so it stays safe. Without RNA, proteins could never be made.
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