which of the following foreshadows the destruction to come???

Answer:
The motif of death and disease.
Explanation:
Foreshadowing is a literary hint that a writer gives to indicate what is to come in a story. Often it appears at the beginning of a story to increase the reader's appetite and expectations about a future event. To foreshadow the destruction to come implies that an hint has been given for the expectation of a terrible unexpected occurrence.
Shakespeare's Hamlet personifies death as a shadow, and depicts disease by madness. Hamlet's father appeared to him in the form of a ghost to foretell his murder, which foreshadows Hamlet's descent into madness. This ignited a rage within him which led to the death of his uncle, mother, and himself.