The option where clause 2 is dependent on Clause 1 is D. Padmi looks frantically for her pen while her sister calmly writes with it.
It should be noted that Clause 1 is that Padmi looks frantically for her pen while Clause 2 is that her sister calmly writes with it.
Therefore, in the sentence "Padmi looks frantically for her pen while her sister calmly writes with it", clause 2 depends on clause 1.
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