Non-steroid hormones are made of amino acids, so they are
proteins.
The statement is true.
Non-steroid hormones are derived from amino acids. Along with norepinephrine
and epinephrine, they are hormones called amines, since amino acids make up proteins;
they are considered proteins which are synthesized in the inner part of adrenal
gland or the adrenal medulla.
Non-steroid hormones are water soluble thus, they do not enter the cell, but
instead, they bind to plasma membrane receptors, creating a second messenger or
a chemical signal inside the target cell.