Question

So in general what rule can you make about substances that dissolve in solvent?

Answer 1

In general, SOLUBILITY is an ability of a substance to dissolve. In the process of dissolving, the substance which is being dissolved is called a solute and the substance in which the solute is dissolved is called a solvent. A mixture of solute and solvent is called a solution.

Answer 2

Can I ask you something? Are you talking about polar and non polar solvents? If so, then it's quite simple. Polar solutes dissolve in polar solvents and non polar solutes dissolve on non polar solvent. Hope it's helpful. If not, let me know.