Respuesta :
It is the receptor mediated endocytosis process. The botulinum toxin, by binding to a receptor, promotes the creation of a vesicle of endocytosis in the axon terminal incorporating the toxin. The part that connects to the receptor is a heavy chain from the toxin and the part that will further preform the action of the toxin is a lighter chain that will be realised once the toxin is inside the neuron.
The vesicular transport process that is involved in the toxin entering the neuron is the receptor mediated endocytosis process.
Further Explanation:
Endocytosis is the process by which some particles are taken in by a cell by the process of invigoration of its membrane and formation of a vacuole. The receptors are the molecules present on the cell membrane that acts as a transmitter of information. Receptors are protein-based substances that are usually integrated into the biological systems.
In the receptor-based endocytosis process, the receptor that is present on the cell membrane is specific to an extracellular molecule which is termed as ligand. The receptor recognizes only a ligand and further binds to it. This binding induces reactions in plasma membrane and the complex stimulates the process of vesicle formation in the plasma membrane. The vesicle engulfs the receptor ligand complex and the process completes. The botulinumtoxin is a protein that is neurotoxic in nature and is produced by Clostridium botulinum. The neurotransmitter acetylcholine's release is blocked by this neurotoxic protein causing flaccid paralysis.
The question depicts that the toxin incorporates into the axon end by the formation of a vesicle. The functions of the toxin are for the carried out inside the neuron.
Thus, the vesicular transport process that is involved in the toxin entering the neuron is the receptor mediated endocytosis process.
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Answer Details:
Grade: High School
Subject: Biology
Chapter: Nervous System
Keywords:
Vesicular transport, receptor, endocytosis, receptor mediated endocytosis, clostridium botulinum, toxin, neurotoxin, neuron, axon, plasma membrane, paralysis, acetylcholine, neurotransmitter.
