The Athenian Acropolis, a temple complex dedicated to Athena, was destroyed by the Persians under the command of Xerxes in roughly 480 BCE during its long construction time. Perseopolis was capital of the Persian empire, and it would make sense that Alexander would burn it to the ground as revenge for the earlier attack against the Greek sacred space.
The remaining portions of the Acropolis ruins we are familiar with now were actually built AFTER Xerxes sacked Athens and the Persians were driven out of the city.