The correct answer is D. because one of the witches' prophecies has come true.
At the beginning of the play, a witch made a prophecy about Macbeth - she told him that he will become king soon, but that he will die when the Birnam Wood comes near his castle. He scoffed at this because he thought this was impossible, but when that actually happened, he started fearing for his life (and he did die in the end).