What issue was the most important cause of the split between the eastern and western halves of the Christian church? 1 Should Greek or Latin be used in church services? 2 Should the pope be supreme in church affairs? 3 Should a crusade be declared against the Muslims in Palestine? 4 Should all religions be tolerated in the empire?
"D. Should the pope be supreme in church affairs?" was the most important cause of the split between the eastern and western halves of the Christian church, since many started questioning his ultimate wisdom.