A man is exposed to large amounts of ultraviolet radiation while sunbathing at the beach. This exposure causes a genetic change in the DNA of a skin cell. In the future, this change can be passed on to (1) his male and female children (2) his male children, only (3) all cells in his body (4) his skin cells, only

The DNA in skin cells that are directly exposed to the sun is harmed by ultraviolet (UV) radiation. Thymine dimers, which are aberrant covalent connections between neighboring thymine nucleotides in the DNA strand are what are responsible for this damage. These dimers have the potential to interfere with DNA's normal structure and functio resulting in cell mutations.

Therefore, The genetic modification will only affect the skin cells that are directly exposed to UV radiation the other cells in his body will not be affected.

Therefore, option 4, his skin cells only.