According to the U.S. Census Bureau, as of March 2014 there are approximately 7,150,000,000 people living in the entire world and 317,700,000 living in the U.S but these numbers change continuously.
Divide the number of people in the U.S. by the number of people in the world and multiply by 100 to get the answer.
= 317700000 / 7150000000 x 100
= 4.44%