The answer to the question above is CYTOPLASM. This is the part of the cell wherein the pigment, bilirubin, can accumulate. Bilirubin is actually one of the major components of bile along with bile acids. The manifestation of jaundice means that there is a retention of bilirubin. This pigmentation can then be accumulated at the cytoplasm. The cytoplasm is the part of the cell which comprises the more specific parts that are outside of the nucleus.