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Fever ________. is a higher-than-normal body temperature that is always dangerous production is regulated by chemicals that reset the body's thermostat to a higher setting causes the liver to release large amounts of iron, which seems to inhibit bacterial replication decreases the metabolic rate of the body to conserve energy

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I believe the correct answer is the second  option. Fever is always dangerous production is regulated by chemicals that reset the body's thermostat to a higher setting. It is a response to an abnormal processes in the body where it affects the body's homeostasis. Oftentimes, it is caused by infection.
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