The Cumberland Gap
A.is located on the border of the Mississippi River.
B.was located in 1750 by Daniel Boone, the first American to do so
C.is another name for the Wilderness Road
D.was created by a stream running through the Appalachians

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Your answer is 100% D. 

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Answer:

its d

Explanation:

was created by a stream running through the Appalachians  hope it helps