Question

Sequencing eukaryotic genomes is more difficult than sequencing genomes of bacteria or archaea because of the _____.

Answer 1

Are there options? because there are lots of answers. 

Firstly, eukaryotic DNA tends to be much longer; it's held inside a nucleus, so it has to be separated from the rest of the cell; and there are also mitochondria in most eukaryotic cells, which have their own RNA, which has to be separated.