A primary follicle enlarges, develops several layers of granulosa cells, and fluid-filled vesicles, it is called a .secondary follicle.
Granulosa cells are interior your ovaries. those cells produce estrogen, progesterone and other hormones. The hormones play a huge component in the lady reproductive machine, from menstruation to ovulation to egg implantation.
A follicle that has two layers of follicular cells is called a number one follicle. those cells hold to hypertrophy and proliferate to shape many layers surrounding the oocyte. eventually those cells turn out to be referred to as 'granulosa' cells. The granulosa cells will secrete progesterone after ovulation.
Theca and granulosa mobile cooperation in estrogen synthesis. Theca cells produce androgens in response to luteinizing hormone (LH). Granulosa cells respond to follicle-stimulating hormone (FSH) mainly by means of aromatizing androgens to estrogens and to a degree by generating pregnenolone from ldl cholesterol.
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