The substance that increases the inflammatory response and the secretion of mucus following exposure to an allergen is Histamine.
Mast cells release excessive amounts of Histamine during an allergic reaction, which is the immune system's hypersensitivity reaction to normally benign foreign substances (known as antigens in this context) that penetrate the body. Histamine causes an inflammatory response by increasing blood flow to the injured area.
Histamine is a biologically active substance that is found in many living organisms. It is widely distributed, though somewhat inconsistently, all through the animal kingdom and is found in many plants, bacteria, and insect venom. According to the structure of ammonia, histamine is categorized as an amine, an organic molecule. It is formed when the amino acid histidine is decarboxylated (a carboxyl group is removed).
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