Because of the aberrant hemoglobin, red blood cells become stiff and sticky and resemble the C-shaped "sickle" farm implement. The early death of sickle cells results in a persistent lack of RBC.
By analyzing blood under a microscope, diseases such as bacteria, fungus, and parasites can be found.
The surface morphology of the blood sample can be seen with a scanning electron microscope at increased magnification (SEM). Transmission electron microscopes (TEM) are used to examine blood cells on a cellular level.
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