Question

Review Email i and then write an email to Tess identifying the first messenger that starts the signal transduction in the smooth muscle cell, the likely second messenger, and finally the cellular response caused by the cell signaling cascade. Explain why the arrows go from small to bigger. Also identify whether the receptor that starts the cell signaling pathway is in the plasma membrane or intracellular. Review Email 2 and then answer the following questions: 1. Melody said that ginseng enhances erection. What effect would you expect ginseng to have on nitric oxide? Why? 2. Knowing that Melody said Viagra also enhances erection, what effect would you expect it to have on PDE5? Why? 3. If neither chemical works what protein(s) would you suspect is "broken"?

Answer 1

Increased nitric oxide synthesis may play a role in ginseng's aphrodisiac and ginseng-associated vasodilatation. As signal transduction is amplified at each step, arrows go from small to bigger.

Ginseng's antioxidant and organ-protective properties are linked to increased nitric oxide (NO) synthesis in the corpus cavernosum, heart, and lung endothelium. As a result, Ginseng's aphrodisiac properties and ginseng-associated vasodilatation may be influenced by an increase in nitric oxide production.

Erectile brokenness (ED) is the persevering failure to accomplish or keep an erection adequate for agreeable sexual execution. PDE5 inhibitors are now the first line of ED treatment. The pharmacokinetic properties of PDE5 inhibitors in terms of absorption, distribution, metabolism, and excretion have been investigated.

Sildenafil is a powerful and particular inhibitor of cGMP explicit phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is liable for the debasement of cGMP.

Know more about PDE5 inhibitors here: https://brainly.com/question/29315180

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