Trans-acting regulators of gene expression include histone deacetylases. Correct answer: letter E.
This is because they can influence chromatin structure and subsequently control gene expression. By removing acetyl groups from histone lysine residues, HDACs can cause neighboring histones to bind more tightly, which compacts chromatin and makes it more difficult for transcription factors to access DNA. As a result, gene expression is reduced.
Are molecular components that interact with DNA to control the production of proteins. These regulators act on the transcription level, where DNA is transcribed into mRNA, allowing the expression of the gene in question. Examples of trans-acting regulators of gene expression include:
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