Octreotide is a long-acting synthetic analog of somatostatin.
What is somatostatin?
Somatostatin mostly has neuroendocrine inhibitory effects on a variety of systems. It is known to alter neurotransmission and memory formation in the CNS, as well as to inhibit GI, endocrine, exocrine, pancreatic, and pituitary secretions. Somatostatin is also known by the acronyms SS, SST, or SOM. the hormone that inhibits growth hormone (GHIH). the factor that prevents the release of somatotropin (SRIF). somatotropin-releasing hormone inhibitor (SRIH). The pancreas also secretes somatostatin in response to various dietary-related conditions, including elevated blood levels of amino acids and glucose—the powerful inhibition of insulin and glucagon release from pancreatic islets by somatostatin (SST). There are five different SST membrane receptors (SSTR1–5), and at least two of them have been suggested to control pancreatic endocrine function.
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