Question

RNA polymerase enzymes in general do not have proofreading functions. In contrast, DNA polymerase enzymes often do have proofreading functions. Using this information, compare the following types of viruses and indicate which would you could reasonably predict to have the LOWEST mutation rate.
a) Group 2
b) Group 3
c) Group 4
d) Group 5

Answer 1

C. Group 4 is the right option. Because RNA molecules are working copies that can tolerate a few errors, it is commonly accepted that RNA pol. does not need to proofread.

The polymeric molecule ribonucleic acid (RNA) plays numerous biological roles in the coding, decoding, regulation, and expression of genes. The two types of nucleic acids are RNA and DNA. The four main macromolecules required for all known forms of life are lipids, proteins, carbohydrates, and nucleic acids. The building blocks of RNA are nucleotides, just like DNA, however unlike DNA, RNA exists in nature as a single strand folded over itself rather than a paired double strand. Using the nitrogenous bases guanine, uracil, adenine, and cytosine, cellular organisms use messenger RNA (mRNA) to transmit genetic information.\

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