After a virus connects to a particular host cell receptor, it either enters the cell by integrin endocytosis or by fusing with the target cell's plasma membrane.
The viral life cycle's first step of infection, known as viral entry, occurs when the virus gets in contact with the host organism & introduces viral material there. Initial contacts between viruses and cell membranes occur independently of fusion proteins. The virus fusion proteins finally connect to specific receptors on the cellular membrane as the virus moves all along fluid cell's outer surface (4). The two membranes will continue to be separate if merely binding took place. The viral particle must first engage in non-covalent contacts with one or more of the receptor-specific viral replication anchored into to the lipid bilayer before it can infect a new cell.
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