All of the following statements are true. Which one statement describes the biggest impact that sickle-cell disease has over the organs and organ systems of the body?Mutated hemoglobin molecules result in misshapen red blood cells that cannot function to transport oxygen in the body.

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Organ injury. sickle-shaped red blood cells as a result of mutated hemoglobin proteins. Sickle cells that restrict blood flow deplete organs of both oxygen and blood. In sickle cell anemia, blood oxygen levels are also abnormally low. This deficiency in oxygen-rich blood can be lethal and harm nerves and organs including the kidneys, liver, and spleen.

The most frequent cause of Sickled cells complications and the main reason patients with Sickled cells visit the ER or hospital is pain. Sickled cells can become caught and impede blood flow throughout the body when moving via tiny blood veins, which hurts.

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