Question

When Ras is activated, cells will divide. A dominant-negative form of Ras clings too tightly to GDP. You introduce a dominant-negative form of Ras into cells that also have a normal version of Ras. Which of the following statements is true?
(a) The cells you create will divide less frequently than normal cells in response to the extracellular signals that typically activate Ras.
(b) The cells you create will run out of the GTP necessary to activate Ras.
(c) The cells you create will divide more frequently compared to normal cells in response to the extracellular signals that typically activate Ras.
(d) The normal Ras in the cells you create will not be able to bind GDP because the dominant-negative Ras binds to GDP too tightly.

Answer 1

The correct answer (a) The cells you create will divide less frequently than normal cells in response to the extracellular signals that typically activate Ras.

Ras protein is a low-molecular-weight GDP/GTP-binding guanine triphosphatase produced by the Ras gene that plays an important role in cell growth and differentiation signaling. In the regular course of signal transduction.

What is the function of the RAS protein?

RAS proteins play a crucial role in proper development. Active RAS promotes cell growth, proliferation, and migration. RAS in normal cells receives and obeys signals to swiftly flip between active (GTP form) and inactive (GDP form) states.

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