In 1958, Meselson and Stahl conducted an experiment to determine which of the three proposed methods of DNA replication was correct. Identify the three proposed models for DNA replication. Conservative Semiconservative Dispersive . Answer Bank The Meselson and Stahl experiment starts with E. coli containing 1sN/SN labeled DNA grown in 14N media. Which result did Meselson and Stahl observe by sedimentation equilibrium centrifugation to provide strong evidence for the semiconservative model of DNA replication? O The first generation has hybrid ^15N/^14N DNA and the second generation has both hybrid ^15N/^14N and ^14N/^14N DNA. No ^15N/^15N DNA was observed. O Both the first and second generation have both ^15N/^15N DNA and ^14N/^14N DNA. No hybrid ^15N/^14N DNA was observed. O The first generation has hybrid ^15N/^14N and the second generation has hybrid ^15N/^14N DNA. No ^15N/^15N DNA nor ^14N/^14N DNA was observed.