Yes, Chromosome breakage and abnormal re-attachment is one mechanism that causes a reciprocal translocation. Another mechanism involves a crossover between nonhomologous chromosomes.
Crossover between nonhomologous chromosomes, chromosomal breakage, and DNA repair all results in reciprocal translocations. Chromosomes that do not come from the same pair are referred to as non-homologous chromosomes. In non-homologous chromosomes, the form of the chromosome—that is, the length of the arms and the location of the controller—is generally different. Therefore, meiosis does not result in the pairing of non-homologous chromosomes.
Homologous genes are described as two or more genes that have a common ancestor. In a genetic context, however, they have a more precise meaning: ancestry is knowledge about your ancestors' genetic tie to you. Your ancestors are the people from whom you are biologically related.
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