The stress response is mediated by proteins that are created in response to the cortisol signal. A tiny, hydrophobic steroid hormone called cortisol may cross a cell's plasma membrane.
A hormone receptor complex is created in target cells when cortisol binds to the intracellular receptor protein in the cytoplasm. After entering the nucleus, the hormone receptor complex functions as a transcription factor by binding to certain genes and triggering their transcription into mRNA. In the end, the mRNA generated is translated into certain proteins. Some proteins help raise blood glucose levels, enabling an animal to meet demands of starvation or vigorous exercise.
1. The plasma membrane allows cortisol to enter the cytoplasm.
2. In the cytoplasm, a cortisol-receptor complex hormone develops.
3. The cortisol receptor complex moves into the nucleus and attaches to the genes there.
4. A transcription factor is the cortisol-receptor complex.
5. A particular protein is produced from the transcribed mRNA.
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