The correct option is C : Every gene encodes a separate enzyme. One enzyme, one gene The theory holds that each gene encodes a single enzyme.
We now know that this concept is typically (but not entirely) right. Sir Archibald Garrod, a British medical practitioner, was the first to propose that genes and enzymes were linked.
According to Beadle and Tatum, each gene drives the synthesis of one (and only one) enzyme. Beadle and Tatum shared the 1958 Nobel Prize in Physiology or Medicine with J. Lederberg.
They identified a set of mutations known to disrupt the production of arginine, an amino acid required for mould development. Individual mutations, according to their idea, hindered specific steps in the process utilized by the mould to manufacture arginine from precursors in its surrounding media.
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Full Question :
Which statement is most consistent with the one gene, one enzyme hypothesis originally proposed by Beadle and Tatum?
A Every enzyme makes one gene.
B Genes and enzymes are important.
C Every gene encodes a separate enzyme.
D A gene can only make one enzyme in a cell cycle.
E Each gene makes one enzyme but not one protein.