4-Dimethylaminopyridine is the extended form of DMAP in chemistry. It boils at a temperature of roughly 162 degrees Celsius. A very little over 122 g/mol is the molecular weight.
What is nucleophilic substitution reaction?
When an electron-rich nucleophile replaces a leaving group by coming into touch with a positively charged electrophile, the process is known as a nucleophilic substitution reaction.
Explanation:
Step 1: DMAP and acetic anhydride initially react in a state of pre-equilibrium.
Acetate and acetyl pyridinium ion pair are produced in the first step of the reaction. They both have high resonance stabilization.
Highly electronegative oxygen delocalizes in a structure with equal resonance energy.
Step 2:
DMAP is removed in the second stage when the alcohol that is present combines with the acyl carbon of the acetyl pyridinium to form the ester.
Acetate acts as a base to remove the proton from the alcohol by nucleophilically adding to the activated acyl pyridinium. The catalyst and the ester are produced as a result of the acetyl group's break with the catalyst. The resulting acetic acid will subsequently protonate the DMAP.
Step 3:
In the final stage of the catalytic cycle, the auxiliary base (unusual triethylamine Et N:or pyridine) deprotonated the protonate DMAP, reforming catalysis. The idea of a DMAP-dependent reaction rate is defined by catalepsies.
To learn more about nucleophilic substitution reaction from the given link.
https://brainly.com/question/14052597
#SPJ4
