When the blood pH drops, chemoreceptors in the aorta and carotid bodies activate the brain's respiratory control center.
Chemoreceptors monitor the amounts of hydrogen ions in the blood to determine the quantities of carbon dioxide there.
Peripheral chemoreceptors that detect falling or more acidic pH levels trigger increased ventilation to accelerate the removal of carbon dioxide from the blood. The body's medulla, which houses the body's respiratory center, is typically stimulated by an increase in carbon dioxide concentration and, to a lesser extent, by a decrease in oxygen levels in arterial blood.
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