Sir Archibald Garrod, a British physician, was the first to postulate a link between genes and enzymes.
Who made the decision that genes dictate which enzymes exist?
As demonstrated by Beadle and Tatum, genes specify enzymes. It was discovered that several enzymes were absent in Neurospora mutants unable to produce arginine. The "one gene/one polypeptide" theory was advanced by Beadle and Tatum. According to the core dogma, information travels through cells from DNA to RNA to proteins.
Who made the connection between DNA and proteins known?
The discovery that the four bases of DNA, which at first glance appeared to be randomly arranged, actually formed a code dictating the arrangement of the twenty amino acids that make up the majority of proteins was made by Watson and Crick.
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