As acetaldehyde dehydrogenase is inhibited by disulfiram, many of the side effects of alcohol use are experienced right away.
Disulfiram functions by preventing the body from breaking down alcohol. This causes a hazardous alcohol-related chemical to accumulate, which can make patients who consume alcohol while taking this drug very ill.
In milder situations, the disulfiram-alcohol interaction lasts 30 to 60 minutes; in more severe cases, it lasts several hours or until the alcohol is digested.
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