If the client has 10 lb weight loss then he/she must discontinue the sulfonamide.
Itching, skin rash, increased sensitivity to sunlight, diarrhoea, headache, loss of appetite, nausea, or vomiting, and weariness are typical adverse effects of sulfonamides.
Dihydropteroate synthase is a particular enzyme that sulfa medicines bind to and block (DHPS). The creation of the important vitamin folate depends on this enzyme. Folate is a nutrient that mammals obtain from their diet, but bacteria must make it.
It is well known that sulfonamides can harm the liver in peculiar ways. Since virtually all sulfonamides used today have been connected to a small number of convincing cases of drug-induced liver injury, hepatotoxicity appears to be a class effect.
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