Intrinsic factor is produced in the stomach and contributes directly to the absorption of vitamin b12.
The body would not be able to absorb vitamin B12 in the small intestine without intrinsic factor, which is produced by gastric parietal cells.
What is Intrinsic factor?
The parietal cells or main cells of the stomach generate the glycoprotein known as intrinsic factor, cobalamin binding intrinsic factor, also referred to as gastric intrinsic factor. Later on, in the small intestine's distal ileum, it is required for the absorption of vitamin B12.
Therefore, Intrinsic factor is produced in the stomach and contributes directly to the absorption of vitamin b12.
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