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The condition is caused by the occlusion and abdominal distension of a lumens, which results in reduced blood flow, ischemic, and bacterial invasion is known as Appendix.

Appendiceal lumen occlusion is frequently the etiology of appendicitis. This may result from an appendicolith (appendix stone). The precise cause of acute pancreatitis is frequently unknown. Bacteria accumulate in the appendix as a result of obstruction of the appendiceal lumen, resulting in acute inflammation, perforation, and abscess formation. Despite being necessary, lymphoid hyperplasia causes swelling, localised ischemic, perforation, and the formation of a confined abscess or a true perforation with subsequent peritonitis.Appendicitis is brought on by an obstruction results in small vessel occlusion, lymphatic stasis, and a rise in luminal and intramural pressure. When blocked, the appendix begins to swell and fill with mucus. As lymph and vascular damage progresses, the appendix wall turns ischemic and necrotic. The restricted space then experiences bacterial overgrowth.

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