The catalase deficiency during Takahara's disease can be diagnosed by: swishing H₂O₂ around the oral cavity and checking for the presence of bubbles.
Catalase is an enzyme that catalyzes the decomposition of H₂O₂ into water and oxygen. It is found in almost all the aerobic organisms. The enzyme is required to protect an organism from the reactive oxygen species. The enzyme in humans is found in their liver.
Takahara's disease is also known by the name acatalasemia. It is the condition in which open soars, also called ulcers appear on the mouth. This leads to the death of soft tissues, a condition called gangrene. It is a rare genetic disorder.
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