Acetylcholine is responsible for the hyperpolarization of the sinoatrial node.
At a specific location on the neuron's membrane, hyperpolarization occurs when the membrane potential increases, and depolarization occurs when the membrane potential decreases (more positive).
Most activities involved in maintaining and functioning of neurons are started at the neuronal membrane. Membrane-related molecular agents, which interact in protein/lipid clusters to start molecular processing and signal transduction, are required for these processes.
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